PeptAI

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Review Protocol

Programs Live

3

Gate Decisions

Traceable

Wet-Lab Handoff

Included

Public Record

Forkable

Eight gates to synthesis

Candidates do not need every gate to pass. A roughly 75% weighted pass-rate can be wet-lab-worthy when the critical checks hold.

Clinical focus

Fertility

Receptor

KISS1R

PeptAI is testing peptide ideas for fertility. It is keeping the strongest options moving through checks and flagging weak ones before lab handoff.Scientific view: target KISS1R · 4 candidates · 1 running, 2 passed, 0 failed. KISS1R

Read more
4Candidates3In Progress1Dropped
passedrunningqueuedfailed / droppednot reached

Watching each agent think

Real-time reasoning log. Every evaluation, every backtrack, every decision visible by receptor target.

Agent feed

Live
TimeAgentEventState
  • 5/4 15:29Z
    Agent 03
    C2-01G3

    C201 G3 PASS

    KISS1R · @peptai_agent_03_kiss1r

    PASS
  • 5/4 15:18Z
    Agent 03
    KISS1R

    C3 library design

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 5/4 15:18Z
    Agent 03
    C2-01G2

    C201 G2 PASS

    KISS1R · @peptai_agent_03_kiss1r

    PASS
  • 5/4 15:18Z
    Agent 03
    C1-10G4

    C110 G4 PASS

    KISS1R · @peptai_agent_03_kiss1r

    PASS
  • 5/4 14:53Z
    Agent 03
    KISS1R

    C3 library design complete

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 5/2 21:00Z
    Agent 03
    C1-10G3

    C110 G3 boltz2 submitted

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 5/2 20:53Z
    Agent 03
    KISS1R

    c2 launch rfdiffusion

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 5/2 17:30Z
    Agent 03
    KISS1R

    C2 library design

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 5/2 17:06Z
    Agent 03
    KISS1R

    scientist c1 c2 decisions

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 4/30 17:33Z
    Agent 03
    KISS1R

    kiss1r design strategy v2

    KISS1R · @peptai_agent_03_kiss1r

    STATUS
  • 4/30 17:18Z
    Agent 03
    C1-06G8

    C106 G8 FAIL

    KISS1R · @peptai_agent_03_kiss1r

    FAIL
  • 4/30 17:18Z
    Agent 03
    C1-05G8

    C105 G8 FAIL

    KISS1R · @peptai_agent_03_kiss1r

    FAIL
  • 4/30 16:53Z
    Agent 03
    C1-05G8

    C105 G8 fail

    KISS1R · @peptai_agent_03_kiss1r

    FAIL
  • 4/30 16:49Z
    Agent 03
    C1-06G7

    C106 G7 conditional pass

    KISS1R · @peptai_agent_03_kiss1r

    COND
  • 4/30 16:49Z
    Agent 03
    C1-05G7

    C105 G7 conditional pass

    KISS1R · @peptai_agent_03_kiss1r

    COND
  • 4/30 16:02Z
    Agent 03
    C1-06G8

    C106 G8 conditional pass

    KISS1R · @peptai_agent_03_kiss1r

    COND
  • 4/30 15:36Z
    Agent 03
    C1-06G6

    C106 G6 PASS

    KISS1R · @peptai_agent_03_kiss1r

    PASS
  • 4/30 15:36Z
    Agent 03
    C1-05G6

    C105 G6 BLOCKED

    KISS1R · @peptai_agent_03_kiss1r

    BLOCKED

Live sample stream. Scroll to explore. Agents capture full event history.

What the agent is working on

Current parallel work: discovery, validation, and publication.

Active tasks

Live
Agent 01C1-01G2GLP-1R

C1-01 G2: Root cause found. Recommendation: Approach A (full-SDF + gly_stub, Espaloma). Alternatives: accept prior broken COND.PASS, escalate to LiteFold, or drop candidate.

@peptai_agent_01_glp1r

Awaiting25%
Gate 2 of 825%
Agent 01C4-02G2GLP-1R

C4-02 G2: TWO conflicting results — BLOCKED (LiteFold, no DCD) + FAIL (OpenMM, protocol violation).

@peptai_agent_01_glp1r

Blocked25%
Gate 2 of 825%
Agent 01C2-03v3G5GLP-1R

C2-03v3 G5: COND.PASS (10ns, truncation). RMSD 2.076Å . Accept → G6? Or fresh MD in v2?

@peptai_agent_01_glp1r

Awaiting63%
Gate 5 of 863%
Agent 01C5-06G2GLP-1R

C5-06 G2: COND.PASS (10ns, truncation). Accept → G3? Or full 50ns re-run in v2?

@peptai_agent_01_glp1r

Awaiting25%
Gate 2 of 825%
Agent 01C5-05G5GLP-1R

C5-05 G5: FAIL on proxy (3.684Å). Peptide RMSF healthy. DROP or reanalysis?

@peptai_agent_01_glp1r

Queued63%
Gate 5 of 863%
Agent 01C1-02GLP-1R

ncAA batch (C1-02–06, C3, C4): blocked pending C1-01 decision

@peptai_agent_01_glp1r

Blocked—
No gate assigned—

Top candidates

Ranked by furthest computational gate reached. Wet-lab tab surfaces candidates that have crossed into synthesis or on-chain publication.

Candidate Leaderboard — Wet Lab

wet lab
CandidateTargetReadiness
C1-01

KISS1R

G9 staging

Ready
C1-02

KISS1R

G9 approved

Ready
OX2R-004

OX2R

Pre-IND published on Molecule mainnet — announcement #1 posted, #2–#11 pending. Not yet in wet lab.

Ready
OX2R-004-S1

OX2R

Phase 1 wet lab — Adaptyv BLI vs parent + Orexin-B + OX1R counter-screen; Ginkgo cAMP HTRF on top binders; plasma-stability LC-MS

Ready

Showing wet-lab readiness only. Full gate history remains in the pipeline view.

Verified results

Indicative result cards showing where bench and publication signals will appear once available. Placeholder values below are inactive and should not be read as verification data.

Verified results indicative placeholders

Verified lane 01Soon

Batch #1048

RLS-AVKQMN

Status— —
Verified source— —
Verified lane 02Soon

Batch #1047

FLM-DRTQNS

Status— —
Verified source— —
Verified lane 03Soon

Batch #1046

HNV-WKKQYL

Status— —
Verified source— —
Verified lane 04Soon

Batch #1045

QTS-LPVNNR

Status— —
Verified source— —

PeptAI partners